Session 2 : Translational Science

Translational Science by Manish Singhal

Chairpersons :

Ramesh Nimmagadda, R K Deshpande

Speaker :

Manish Singhal

Efficacy and tolerability of veliparib (V; ABT-888) in combination with carboplatin and paclitaxel (P) vs placebo (Plc)+C/P in patients (pts) with BRCA1 or BRCA2 mutations and metastatic breast cancer: A randomized, phase 2 study

Author: Han HS

Conference: 2016 SABCS S2-05

DNA repair deficiency biomarkers and MammaPrint high1/(ultra) high 2 risk as predictors of veliparib / carboplatin response: Results from the neoadjuvant I-SPY 2 trial for high risk breast cancer

Author: Wolf DM

Conference: 2016 SABCS S2-06

Adaptive Randomization of Veliparib-Carboplatin Treatment in Breast Cancer

Author: HS Rugo

Reference: N. Engl. J. Med; 2016 Jul 7; 375(1)23-34